TxDOT says all lanes on I-2 are now open.
The Texas Department of Transportation says the eastbound lanes of I-2 are now open.
Officials advise that the westbound main lanes remain closed in the Valverde area.
Drivers are advised to find alternate routes.
Alamo officials are advising of lane closures on the expressway due to a major accident.
According to authorities, an 18-wheeler is sprawled across the east and westbound of the expressway.
Delays are expected to last from 2 to 4 hours said authorities.
No injuries have been reported.
The Texas Department of Transportation said traffic is being rerouted to Frontage Road.
CBS 4 will update this story as more details become available.